About This Digest

What Peptide Division is

Peptide Division is an independent editorial digest covering the published research literature on three peptides that share a mechanism territory: the growth hormone axis. The three — ipamorelin, CJC-1295, and sermorelin — all stimulate the anterior pituitary to release growth hormone, but they do so by different receptors, with different durations, and with very different evidence histories. The site exists to make those distinctions readable and honest, rather than flattening them into a single "GH peptide" category as most popular sources do.

The organizing frame is the GHRP-versus-GHRH contrast. Ipamorelin activates the ghrelin/GHS receptor (GHRP mechanism); CJC-1295 and sermorelin activate the GHRH receptor directly. That mechanistic distinction matters for how the compounds behave, how they are sometimes combined, and why the evidence base for each looks different. Each compound has its own page; a comparison page lines them up; a single shared references list aggregates every cited source across all three.

How it is compiled

Three principles govern what appears here.

Peer-reviewed anchoring. Every research claim is tied to a numbered citation — PubMed-indexed journal articles, published reviews, and regulatory documents — collected on the references page. Where a finding comes from a review rather than a primary study, that framing is stated explicitly.

Evidence reported at its actual strength. Doses are described in the species and route in which they were studied — for example, "studied at 30 micrograms per kilogram subcutaneously in healthy adult volunteers" — never scaled or converted to a recommendation. Where evidence is animal-only, short-term, from a single group, or rests on a related but distinct compound, the page says so. The absence of efficacy evidence for a given use case is stated plainly, not softened into a "more research is needed" hedge.

Cross-referencing between mechanisms. Because the compounds share downstream targets and are sometimes discussed as a combination, the pages link to one another so a reader can follow a mechanistic question — the GH pulse, IGF-1 feedback, pulsatility preservation — across all three.

What it is not

Peptide Division is not a store, not a clinic, and not a source of medical advice. It does not sell, supply, source, or broker any research peptide or chemical, and it has no affiliate or referral relationship with any vendor. It does not employ clinicians, diagnose conditions, or prescribe anything.

It does not provide a dose, schedule, or route of administration for any person. The doses that appear in these pages are study parameters — the amounts used in specific published protocols in specific populations — and they are recorded because they document what was actually studied, not because they are recommendations for replication.

The peptides here are research compounds. None is currently approved for general adult use; several have nuanced or contested regulatory positions that this desk works to describe accurately rather than simplify. Readers with health questions should consult a licensed clinician in their jurisdiction. The value this site offers is a careful, accurate reading of the published literature — nothing more and nothing it claims to be.